{"id":22561,"date":"2013-07-08T10:01:14","date_gmt":"2013-07-08T14:01:14","guid":{"rendered":"http:\/\/webapp2.wright.edu\/web1\/newsroom\/?p=22561"},"modified":"2015-03-05T16:14:51","modified_gmt":"2015-03-05T21:14:51","slug":"wright-state-researcher-discovers-mechanism-to-slow-tumor-growth-and-metastasis-in-breast-cancer","status":"publish","type":"post","link":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/2013\/07\/08\/wright-state-researcher-discovers-mechanism-to-slow-tumor-growth-and-metastasis-in-breast-cancer\/","title":{"rendered":"Wright State researcher discovers mechanism to slow tumor growth and metastasis in breast cancer"},"content":{"rendered":"<p><a href=\"http:\/\/webapp2.wright.edu\/web1\/newsroom\/2011\/05\/25\/noted-author-samuel-shem-to-deliver-commencement-address-at-the-wright-state-university-boonshoft-school-of-medicine\/bsom_logo\/\" rel=\"attachment wp-att-5107\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-5107\" src=\"http:\/\/webapp2.wright.edu\/web1\/newsroom\/files\/2011\/05\/BSOM_logo-260x204.jpg\" alt=\"\" width=\"260\" height=\"204\" \/><\/a>Wright State University Boonshoft School of Medicine professor Julian Gomez-Cambronero, Ph.D., and his research team have discovered a key protein that plays a critical role in the development of breast cancer tumors and the spread of the disease to the nearby lungs.<\/p>\n<p>Cambronero\u2019s findings, published this month in the leading cancer journal <em>Oncogene<\/em> (click <a href=\"http:\/\/www.nature.com\/onc\/journal\/vaop\/ncurrent\/full\/onc2013207a.html\">here<\/a> for the report), attribute the cancer\u2019s growth to a protein called Phospholipase D (PLD). Cambronero and his team found that by introducing two new chemical inhibitors of PLD they could shrink tumor growth and reduce subsequent metastasis by around 70 percent.<\/p>\n<p>\u201cAlthough it\u2019s still early to tell, the application of these inhibitors to research in human tissue is the next step that could lead to better, less toxic treatments in the battle against breast cancer,\u201d said Cambronero, a professor of biochemistry and molecular biology.<\/p>\n<p>Breast cancer kills more women in the United States each year \u2014 about 40,000 \u2014 than any other type of cancer, according to the National Cancer Institute. The disease strikes an estimated 232,340 females each year and 2,240 males.<\/p>\n<p>Since joining Wright State in 1995, Cambronero and his laboratory have garnered more than $6 million in research funding from the National Institutes of Health, the American Heart Association, the American Cancer Society and other state and federal sources.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wright State University Boonshoft School of Medicine professor Julian Gomez-Cambronero, Ph.D., and his research team have discovered a key protein&#8230; <a href=\"https:\/\/webapp2.wright.edu\/web1\/newsroom\/2013\/07\/08\/wright-state-researcher-discovers-mechanism-to-slow-tumor-growth-and-metastasis-in-breast-cancer\/\" class=\"morelink\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":34,"featured_media":5107,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[722,2100,711,725,4265,2016,715,18,719],"tags":[],"class_list":["post-22561","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-academics","category-biochemistry-and-molecular-biology","category-faculty-staff","category-home-news-sidebar","category-research-medicine","category-medicine","category-news","category-research","category-special-categories"],"_links":{"self":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts\/22561","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/users\/34"}],"replies":[{"embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/comments?post=22561"}],"version-history":[{"count":8,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts\/22561\/revisions"}],"predecessor-version":[{"id":25667,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts\/22561\/revisions\/25667"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/media\/5107"}],"wp:attachment":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/media?parent=22561"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/categories?post=22561"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/tags?post=22561"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}