{"id":45358,"date":"2017-04-28T10:39:03","date_gmt":"2017-04-28T14:39:03","guid":{"rendered":"http:\/\/webapp2.wright.edu\/web1\/newsroom\/?p=45358"},"modified":"2017-04-28T10:40:15","modified_gmt":"2017-04-28T14:40:15","slug":"scholarships-help-medical-student-pursue-dream-of-research","status":"publish","type":"post","link":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/2017\/04\/28\/scholarships-help-medical-student-pursue-dream-of-research\/","title":{"rendered":"Scholarships help medical student pursue dream of research"},"content":{"rendered":"
\"\"<\/a>

Sabrina Metzger is an M.D.\/Ph.D. student at the Wright State University Boonshoft School of Medicine.<\/p><\/div>\n

Fainting goats make for funny YouTube videos. But for the humans who share the same disease, myotonia congenita, muscular dysfunction is no laughing matter.<\/p>\n

The disease is rare in humans, occurring in one of every 50,000. Unfortunately, there are few options for treatment.<\/p>\n

Sabrina Metzger, an M.D.\/Ph.D. student at the Wright State University Boonshoft School of Medicine<\/a>, is using muscle models in a search for more targeted treatments. By using the computational models she\u2019s developing, it may be possible to know sooner which treatments are worth pursuing.<\/p>\n

\u201cThe disease is caused by a mutation that results in muscle stiffness. The patient’s\u2019 muscles don\u2019t relax normally after voluntary movement,\u201d said Metzger, a native of Camden, Ohio. \u201cFor example, if they clench their hands very tightly, they can\u2019t open them for several seconds. Or, say they close their eyes tightly, it\u2019s several seconds until they can open their eyes again. It\u2019s a frustrating and potentially dangerous situation for the patients, and there just aren\u2019t good treatment options available for them yet.\u201d<\/p>\n

Others in the lab of Mark Rich, M.D., Ph.D., professor of neuroscience, cell biology and physiology<\/a> and professor of neurology, are also studying the disease. Where Metzger\u2019s work comes in is its potential to streamline the discovery process.<\/p>\n

The models provide an entirely separate way of approaching the study of the disease.<\/p>\n

\u201cBy using these computer models, we can potentially reduce the number of in vivo experiments, and therefore the cost. The models allow us to gain insight into the mechanisms underlying the disease with much less time and expense,\u201d Metzger said. \u201cThe main thing is that we\u2019re trying to figure out what the best ways are to target the disease. That\u2019s what we\u2019re looking for.\u201d<\/p>\n

Her research is supported through the M.D. tuition scholarship and a Ph.D. tuition waiver and stipend. The awards have helped immensely, as Metzger is a nontraditional student. Without the scholarships, she wouldn\u2019t be able to focus as intently on her research.<\/p>\n

\u201cThere\u2019s no way I could be doing what I\u2019m doing without it. I came in a lot later than other students. I\u2019m at a different stage of life,\u201d Metzger said. \u201cThe great thing is to be able to take the time to focus on my research.\u201d<\/p>\n

In the M.D. program, Metzger saw that there was less time for conducting the sort of in-depth study she sought. Having the option to complete her Ph.D. in the middle of her medical training allows her to do more intensive research and provides more choice in her future career.<\/p>\n

\u201cIt was a huge relief. Getting a Ph.D. gives me a lot more opportunities down the road,\u201d said Metzger, who is considering a future in clinical care or lab research. \u201cHaving this kind of opportunity is amazing. It truly makes a world of difference.\u201d<\/p>\n

The Combined M.D.\/Ph.D. Program<\/a> is a joint program administered through the Boonshoft School of Medicine and the College of Science and Mathematics<\/a>. It reflects the strong interrelatedness of scientific disciplines in medical research today, encompassing areas of clinical, biological, physical and computational sciences.<\/p>\n

For giving opportunities that support students at the Boonshoft School of Medicine, visit medicine.wright.edu\/community\/giving-opportunities<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Sabrina Metzger, an M.D.\/Ph.D. student at the Boonshoft School of Medicine, is searching for targeted treatments for myotonia congenita. Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":53,"featured_media":45359,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[722,2040,725,4265,2149,2016,2115,715,18,746],"tags":[],"class_list":["post-45358","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-academics","category-giving","category-home-news-sidebar","category-research-medicine","category-medical-students","category-medicine","category-neuroscience-cell-biology-and-physiology","category-news","category-research","category-science-mathematics"],"_links":{"self":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts\/45358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/users\/53"}],"replies":[{"embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/comments?post=45358"}],"version-history":[{"count":2,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts\/45358\/revisions"}],"predecessor-version":[{"id":45362,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/posts\/45358\/revisions\/45362"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/media\/45359"}],"wp:attachment":[{"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/media?parent=45358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/categories?post=45358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/webapp2.wright.edu\/web1\/newsroom\/wp-json\/wp\/v2\/tags?post=45358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}